Detecting consistent patterns of directional adaptation using differential selection codon models
نویسندگان
چکیده
منابع مشابه
Detecting Adaptation in Protein-Coding Genes Using a Bayesian Site-Heterogeneous Mutation-Selection Codon Substitution Model
Codon substitution models have traditionally attempted to uncover signatures of adaptation within protein-coding genes by contrasting the rates of synonymous and non-synonymous substitutions. Another modeling approach, known as the mutation-selection framework, attempts to explicitly account for selective patterns at the amino acid level, with some approaches allowing for heterogeneity in these...
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ژورنال
عنوان ژورنال: BMC Evolutionary Biology
سال: 2017
ISSN: 1471-2148
DOI: 10.1186/s12862-017-0979-y